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At least five people are dead and dozens reported injured after an Amtrak train on the way from Washington, D.C. to New York crashed near the Frankford neighborhood in Philadelphia.

The incident was classified as a mass casualty incident, and Mayor Michael Nutter told press that “it is an absolute disastrous mess,” adding that he has “never seen anything like this.”

More than 200 police personnel were on scene as of about 11:30 p.m. and 53 victims of the crash — six in critical condition — were transported to area hospitals. City officials have indicated that 10 trains completely derailed from the tracks, but are not speculating at all on the cause of the incident.

The scene remains dangerous. Officials could not definitively say that all passengers were confirmed as off the train as of about 11:45 p.m. Nutter said police and fire department workers still need to compare manifest information with their records.

Family and friends of anyone on the train should call 1-800-523-9101 for updates on the situation. The federal government is also reportedly already investigating.

Here’s a look at what went down, and what we know so far:

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Chris Krewson is the executive director of LION Publishers, a national nonprofit association that serves local journalism entrepreneurs build sustainable news organizations, and the founding editor of...